Copper-Peptide Creams for Skin Renewal

Copper-peptides are used clinically for wound healing, increased skin healing after laser resurfacing and chemical peels, and for improving the success of hair transplantation. They help stimulate the skin's regenerative processes which repair the skin's protective outer barrier, increase new capillary formation (angiogenesis), increase the production of collagen and elastin which improve skin elasticity and firmness, and increase the water-holding proteoglycans and glycosaminoglycans (GAGs) which hold moisture in the skin and are the only "true" moisturizers of skin. They also activate the skin's system (called metalloproteinases) that removes damaged proteins such as in scars and sun damage marks.

        Copper-peptides also improve the skin's anti-oxidant defenses by activating superoxide dismutase (SOD), a protein which detoxifies free radicals and that is the body's primary anti-oxidant defense. Normally SOD lacks enough copper to be active and copper-peptides, by supplying nutritional copper to SOD, increase the activity of SOD.

        When creams containing copper-peptides are applied to the skin, only very small amounts of the copper-peptides penetrate into the skin. Copper-peptides have passed numerous safety tests. Scientific studies of copper-peptides have found that the amount of copper taken into the body from such copper-peptide creams is insignificant and does not raise total blood copper levels.  However, the microscopic amount of copper-peptide that does enter the skin's upper layer is sufficient to help stimulate skin regeneration.

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http://www.anagen.net/glicolin.htm

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aloe vera gel, copper peptides (hydrolyzed soy protein and copper chloride)

http://www.4skinbeauty.com/

Copper Peptide/DMAE Serum

In clinical studies, copper peptide serum, has shown to be superior to Retin-A and Kinerase in the treatment of lines, wrinkles, collagen renewal, age-spot fading and regeneration of the skin’s elasticity. Copper is also an extremely effective treatment in fading acne marks.

Copper peptides are neutralized by Vitamin C products and vice versa. Using copper peptides and topical vitamin C (ascorbyl palmitate, for instance) together will render each ineffective.

==================== (Above and below- be careful about WHAT IS MIXED TOGETHER)

http://dianayvonne.zoovy.com/category/18.sunscreenchemicals

Titanium vs. Zinx Oxide: ''Zinc Oxide may be OK but the sweat from your skin breaks it down into zinc ion, this could react with the copper ions and reduce effectiveness of copper peptide products. So I think that titanium dioxide is better to use with copper peptides".

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ALSO AN ANTI-FUNGAL:

http://www.pharmcast.com/Patents100/Yr2004/July2004/072704/6767552_Fungal072704.htm

Capable of releasing species, such as ions, which are soluble in the monomer composition and provide the anti-fungal effect. Thus such compounds either themselves are, or provide, the anti-fungal agent. Such suitable non-polymer-complexed materials include, but are not limited to, metals and metal compounds. Examples of such metal compounds or elemental metals include, but not limited to

copper peptides

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Skin remodeling effects make copper peptides better for safer suntanning:

http://www.suntanscience.com/

What are skin remodeling copper peptides?

Protect & Restore Suntanning Lotion contains skin remodeling copper peptides. The only skin remodeling copper peptides in skin products are those from Skin Biology, Neutrogena and ProCyte. These are products that have credible, published, scientific evidence of effectiveness. Other companies do sell copper peptide skin products; however, our tests of many of these products find little or at best marginal activity on skin. Some of these actually inhibit skin repair. Others use peptides from yeast or bacteria that are known to cause skin allergies and asthma in sensitive persons.

Some of the companies that sell these types of copper peptides have been repeatedly fined by the US Federal Trade Commission for false advertising. The word phrase "clinically proven" is a meaningless term in advertising and can mean virtually anything. For more information on various copper peptides, please visit Comparing Copper Peptides

"The Turn Back the Clock Doc", Loren Pickart has spent his life working on methods to reverse the effects of aging in the human body. He is the discoverer of the role of remodeling copper peptides on the repair of human skin and other tissues such bone, hair follicles, liver, stomach lining, and the intestinal tract after his isolation of the human skin remodeling copper-peptide, GHK-Copper from human blood. Skin remodeling copper peptides are the body's natural signals that repair and restore damaged and aged tissue by (1) inducing strong anti-inflammatory actions (activate superoxide dismutase and decrease damaging actions of TGF-beta and interleukin-1), by (2) stimulating the removal of damaged and older skin by increasing the synthesis of metalloproteinases, and (3) by increasing the generation of new collagen, elastin, proteoglycans, and rebuilding the microcirculation and by increasing production of new skin cells. He and his wife, Charlene, worked to start ProCyte Corporation in 1985 to develop his first generation of GHK-Copper products and Skin Biology in 1994 to create a second generation of more effective, skin remodeling copper peptides.

Products based on Pickart's inventions and GHK-Copper have been marketed by AdviCare, American Crew, Amuchina (Europe), Atelier Esthetique, Bard Medical, BioPharm (Middle East), Creative Nail Design, Johnson & Johnson, Schering AG, Neutrogena, Osmotics, ProCyte, Sigmacon Medical Products (Canada) and Tanox Biosystems (Asia). These include products for Cosmetic Skin Renewal: Neutrogena Visibly Firm Night Cream®, Neutrogena Visibly Firm Eye Cream®, Neutrogena Visibly Firm Moisture Makeup®, Neutrogena Visibly Firm Eye Treatment Concealer®, Neutrogena Visibly Face Lotion®, Neutrogena Visibly Firm Body Lotion®, Visibly Firm Face Lotion SPF 20®, Blue Copper Firming Elasticity Repair®, Climate Extreme Body Repair with Copper Peptide®, Simple Solutions® products (Pure Copper Night Renewal®, Pure Copper Morning Dew®, Ultra Copper Firming Serum®, Pure Copper Eye Repair®, Men Pure Copper® After Shave Moisturizer, Men Pure Copper® Eye Repair), NextDerm Revitalizing Serum®, NextDerm Firming Cream, NextDerm Eye Lift Creme®, NextDerm Microdermabrasion Skin Polisher®, Blue Razor Aftershave®, Neova® Eye Therapy, Neova® Night Therapy Creme®, Neova® Day Therapy, Neova® Body Therapy Lotion®, Neova® Cuticle Therapy, Neova® Antioxidant Therapy Serum with GHK Copper Peptide Complex(TM),  Neova® Cuticle Therapy,  Neova® Therapy Cleansing Bar, Neova® Therapy Mattifying Serum, Neova® Therapy Copper Moisture Mask®, Neova® After Shave Therapy, Neova® Body Scrub, Neova Creme De La Copper®, Neova® Therapy Dual Action Lotion; Nu Glow® Copper Peptide Serum, Nu Glow® Copper Peptide Eye Therapy, Nu Glow® DayTime Therapy, Nu Glow® Copper Peptide NightTime Therapy; for Veterinary Wound Healing: Iamin-Vet Skin Care Gel® and Iamin-Vet Wound Cleanser®. for Wound Healing: Iamin Gel Wound Dressing®, Iamin Impregnated Gauze Dressing®, Iamin Wet Dressing (copper-saline)®, Iamin-2 Hydrating Gel®, and Iamin Wound Cleanser®; for Hair Transplantation and improving the success of hair transplants: GraftCyte® Advanced Hair Restoration Technology: GraftCyte® Concentrated Spray, GraftCyte® Moist Dressings, GraftCyte® Hydrating Mist, GraftCyte® Post-Surgical Shampoo and Conditioner, and GraftCyte® Head Start Single Patient Pack; for Stimulation of Hair Growth and Hair Vitality: American Crew Revitalize Daily Shampoo®, American Crew Revitalize Spray Solution®, American Crew Revitalize Daily Conditioner®, American Crew Revitalizing Serum®, American Crew Revitalize Daily Moisture Shampoo®;  Tricomin® Solution Follicle Therapy Spray, Tricomin® Revitalizing Shampoo, Tricomin® Restructuring Conditioner and Tricomin® Conditioning Shampoo; and for Post-Surgical Skin Healing after laser resurfacing, dermabrasion, and chemical peels: Complex Cu3® Intensive Repair Cream, Complex Cu3® Hydrating Gel, Complex Cu3® Post Laser Lotion, and Complex Cu3® Gentle Face Cleanser.  In addition, human clinical studies of Pickart's inventions for bone healing and healing of intestinal irritations (Inflammatory Bowel Disease or Crohn's disease) have given positive results. He received his Ph.D. in Biochemistry from the University of California at San Francisco. For details on copper-peptide tissue remodeling - see: Copper-Peptide Regeneration.

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Again, I need to stress here that the above information is about EXTERNAL skin improvement only, and this COPPER PEPTIDE NEEDS TO BE MIXED WITH PURE ALOE VERA - not something combined with anything else like UREA (urine) - you can get it straight from the aloe vera plant or even cactus. EVEN THEN, it will not absorb deeply enough into the skin for deep repair work, so DMSO must be added. Nothing else, and make sure you have NO COSMETICS, deodorants or other lotions, etc., anywhere on your body. You could add something like colloidal silver water, if desired, but be very careful about what is added.

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http://www.skinbiology.com/copperhealth.html

Copper's protective and anti-aging actions
Metabolically active copper
The Recommended Daily Copper
Should dietary copper intake be raised to reduce major diseases?
Uptake of Copper from Copper-Peptide products
Anti-oxidant Actions of Copper and Dietary Intake
Copper may reduce some cancers
Copper and Cardiovascular Disease
Immune system function
Copper, Inflammation, and Arthritis
Copper and Osteoporosis
Copper and DHEA
Copper and Pregnancy
Anticonvulsant Activities of Copper Complexes
Copper May Protect from Alzheimer's Disease
Is Longevity in France Due to Copper in Wine and Cooking Pots?

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PAGE UNDER CONSTUCTION:

http://yestheyrefake.net/copper_peptide.htm

Introduction: Copper Peptides 101
What Are Copper Peptides?
Are You A Candidate For Copper Peptide Skincare?
What To Expect At Your Skincare Consultation?
Over The Counter Copper Peptide
Risks & Contraindications of Copper Peptide Products
The Least You Need To Know About Copper Peptide
Related Links
References

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http://www.hbcprotocols.com/products-COP20.html

Copper Peptide Serum
Regenerate collagen and elastin.

Hailing from years of wound-healing research at U.C. Santa Barbara on diabetics, copper peptide serum has been proven to possess a powerful ability to turn on your skin's messenger RNA, thereby rearranging the ensemble of proteins necessary for its own remodeling. The result is angiogenesis; (increased cell and capillary growth) restored moisture, and thicker, firmer skin. Copper peptides also improve the skin's antioxidant defenses by activating superoxide dismutase (SOD), a protein that detoxifies free radicals.
     Note: Human skin regenerates mostly at night, so wait until then to apply Cell Stimulating Serum. And remember, this is a very strong copper-peptide serum, (six times more powerful than Neutrogena's new copper formulation), therefore a little goes a long way, so start slowly and then gradually increase.  Rejuvenate your skins collagen as you increase pheromone production with Copper Peptides 

The Science Behind The Molecule: 

New studies are compelling regarding the effectiveness of copper. In addition to copper being a well-known antioxidant, the ability to help stimulate collagen formation is a second very important issue when it comes to repairing as well as preventing aging skin changes. A study performed upon 20 volunteers showed that after 30 days, the formation of ProCollagen, a precursor of Collagen, increased 70% (shown by skin biopsy) compared with 50% formation from Vitamin C and 40% due to Tretinoin, respectively. This means that Copper Peptide is a highly effective agent in the skin rejuvenation process. 

In the skin, copper helps to: 

1. Stimulate Collagen Formation, diminishing fine lines and firming the skin. 

2. Stimulate Elastin Formation, cutting down on sagging and fine lines. 

3. Stimulate the formation of the extracellular cement between cells, thus improving skin strength, cutting down on fragility.

4. Stimulate the formation of GAGS (glycosaminoglycans). This helps to thicken the dermis resulting in a lessening of sagging and helps firm the skin. 

5. Increase blood vessel formation and oxygenation within the skin. 

6. Act as a potent antioxidant by stimulating the enzymatic function of Superoxide Dismutase. 
   =======================

Overview

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copper peptide made how?

Copper-Peptides also improve the skin's anti-oxidant defenses by activating superoxide dismutase (SOD), a protein which de-toxifies free radicals and that is the body's primary anti-oxidant defense. Normally SOD lacks enough copper to be active and Copper-Peptides, by supplying nutritional copper to SOD, increase the activity of SOD.

(I KNOW THAT DMSO is sort of another version of this!--Cindy)

So what do you do to MAKE IT YOURSELF? I saw above that it is defined as "(hydrolyzed soy protein and copper chloride)

so do we use SOY and COPPER? (Like in pennies?) And putting the DMSO in makes it better, anyway?

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http://www.hydrodermrx.com/pages/838406/page838406.html?refresh=1100232525781

Studies have proven that copper is essential for collagen and elastin in the skin

ProCyte Corporation is a publicly-held healthcare company that is committed to bringing innovation and experience to skin health and wound care market professionals through products that contain its patented GHK and AHK copper peptide technologies. ProCyte's copper peptide technologies utilize a sequence of amino acid carriers for health-essential copper. This unique delivery system mimics the body's natural copper transport mechanisms and has a variety of applications in skin health, tissue repair and hair care...

Less than 1 mg of copper is available in the typical daily American diet. Through a complicated series of exchanges, copper finds its way into the blood system, bound primarily to ceruloplasmin. Copper is utilized by essentially every cell; resulting in the intracellular formation of copper-dependent enzymes - including cytochrome c oxidase (energy production) and superoxide dismutase (antioxidation). Copper is also essential for other enzymes including lysyl oxidase (crosslinking of elastin and collagen) and dopamine beta hydroxylase (catecholamine formation). In the 1970's, scientists isolated a sequence of amino acids (glycyl-L-histidyl-L-lysine; GHK) in human serum that bound copper, and used that initial piece of information to build a peptide copper-based technology with implications in anti-aging and tissue repair processes. Not all copper is the same! Recent studies have shown that copper salts and GHK peptide added separately did not stimulate collagen synthesis. (12) ProCyte’s patented complexation of the GHK peptide to copper has been a dynamic breakthrough in copper therapeutics. Through careful formulation and clinical guidance, ProCyte has been able to develop a number of innovative GHK Copper Peptide products to treat a wide range of conditions. ProCyte conducted and published a number of wound healing clinical studies showing the benefits of GHK-Cu (Iamin®, Prezatide Copper Acetate). (3,4) The activities of the compound were supported by research studies showing positive effects on collagen deposition (5), tensile strength (6), angiogenesis (7), and SOD activity. (8) Published studies on hair growth using a different copper peptide compound demonstrated the positive influence of copper on hair follicle cycle regulation. (9) More recent studies have demonstrated GHK copper’s positive impact in diminishing the appearance of fine lines and wrinkles. (11) Utilizing the knowledge that copper peptides provide an essential function relative to tissue repair and skin health, it is ProCyte's goal to provide the clinician with safe and effective products to enhance the healing outcome of cosmetic surgery and hair transplant procedures, leading to a more effective procedure and improved results.

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(GROWS HAIR, too??)

http://www.anagen.net/tricofin.htm

It is a ProCyte SOD product and it has the base in the Iamin discovery by Dr. Loren Pickart.

It is a spray liquid bottle 180 ml (6 fl.oz).

It is  also used 1 ml / day (6 months of provisioning).

Here are some components:

deionezed water, SD alcol 40B, amodimetlcotone, nonoxynol-10, pantenolo, poliquaternium-11, polisorbato 60, tallowtrimonium chloride, acido citrico, dimetil laurimine isosterate, linoleaminodopropyl etil dimonium etosolfato, triamino copper nutritional complex (alanina/istidina/lisina rame polipeptide HCL), metilparaben, benzetonium chloride, mentolo.

This product is the result of scientific searches  on the copper and on the relations with the skin health.

A meaningful increase of hair in anagen phase has been measured in a 6 month-old clinical study using a copper peptide topical solution.

The preliminary studies have shown:

It is therefore very stimulating of the fibroplastis, of the collagen synthesis  and the enzymatic system that are important for the skin and hair health.

Other characteristic would be that to repair the skin around the follicle and to improve therefore the function of the follicle.

When properly formulated with specific aminoacidis, the copper can have brought directly to the follicles and the surrounding structures.

The SOD in tricomin solution is a "Blue copper peptide".

The products Tricomin solution can be used with effectiveness as supplement to other treatments as Rogaine and Propecia.

Have therefore another source of SOD together with Dr. Proctor products and to the Folligen!

Is Copper Better Than Propecia® for Blocking DHT Production?

Copper ion in the skin is more effective in inhibiting the type 1 form which is primarily producing the DHT that damages follicles and can be administered locally to the skin. Sugimoto et al (Sugimito 1995) found that copper ion is a potent inhibitor of 5-alpha reductase, inhibiting both types of 5-alpha reductase (both type 1 and type 2) that produce DHT and is the only metal to do so. Copper ion inhibits (50% reduction in activity) type 1 alpha reductase at 1.9 micromolar (0.12 micrograms copper ion per milliliter) and type 2 alpha reductase at 19.2 microM (1.2 micrograms copper ion per milliliter). No other metal has these effects.

The application of copper-peptides may provide sufficient copper ion into the hair follicle area to block DHT production in the scalp. Metabolically active copper ion (that is, copper ion free to block 5-alpha reductase) in the human body exists at about 1 microgram per milliliter in the blood and less in the skin. While the uptake of ionic copper from copper-peptides applied to the scalp is very low, human experiments by Prof. John Sorenson (University of Arkansas) have found that they can raise copper ion levels in the skin to the effective level of 1 microgram per milliliter.

Cations inhibit specifically type I 5 alpha-reductase found in human skin

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ALTHOUGH YOU DON'T WANT TO ORDER the product advertised on this webpage- there is UREA, etc., in it, I think it said, I did 'swipe' a section:

http://www.citihealth.com/forsha/neova_.htm

COPPER PEPTIDE TECHNOLOGY