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Questions for Dr. Hibberd Headlines (Scroll down for complete stories):
1. Before I go to sleep, I have to wet my mouth. After I sleep two hours, I awake with an extremely dry mouth, so I repeat the process. This has been going on every two hours for many years, but it seems to have gotten worse during the past few months. I also have sleep apnea. Is there a medication or herb for this condition? — Kenneth S. Sleep apnea is a condition that requires a continuous positive airway pressure (CPAP) device. This compressed air or oxygen device will dry the oral mucosa that is predisposing you to dry mouth. Try adding a humidifying device in line with the device in consultation with your physician or pulmonologist. Dry mouth is a side effect of some blood pressure medications, so consult your physician to see whether he will consider an adjustment. In the absence of other underlying conditions or oral/dental agents you use before bed that may aggravate your symptoms. You might consider a reevaluation with your sleep lab to see whether further adjustments can be made to your sleep apnea treatment regimen. Once this is corrected, your sleep should be sound and your frequent awakening controlled. You may be a good candidate for one of the newer nasal CPAP devices, which are far more comfortable than devices of just a few years ago. Editor's Note: 2. I have a continuous pain in the elbow area of my right arm, which is my dominant arm. We did our own cleanup as a result of Hurricane Ike, which required four days of continuous pulling and tugging on tree limbs and stumps. Since then, I have experienced weakness and pain in that arm that won’t go away. I bought a tendinitis brace that goes around the arm just below the elbow. It helps, but I have continuous pain that’s worse if I use the arm or don’t wear the brace (I even have to sleep in it). I have been told the only way to get rid of this is to get a cortisone shot. Is this true, and are there are side effects to the injection? — Sheryl K. Pain in the elbow after overuse indeed may be from bursitis that usually clears without needing local cortisone injection. Most doctors can diagnose this without testing if you see them reasonably soon after the onset of symptoms. Local cortisone injections may be useful for resistant cases of bursitis that fail conservative management and that are not associated with infection, but cortisone may delay healing when used in fracture or ligament/tendon disruption! An alternative to steroid injection may be iontopheresis in which a physician or orthopedist uses local heat and ultrasound to drive a high-potency topical agent into the affected tissue. The presence of weakness, as well as the extended period you have suffered from pain, are red flags for further investigation. The improvement with splinting suggests a local problem with your forearm/elbow area, as opposed to referred pain from your neck. Your primary or family physician should examine you as soon as possible. If tennis elbow is confirmed, no imaging should be necessary and local cortisone in one form or another may be useful, along with an appropriate splint, until this tendonitis is resolved. That can take as long as six weeks. If your doctor is not sure tennis elbow is the cause of your pain or if ordinary X-rays don’t give a definite diagnosis, consider an MRI (provided that you don't have any metallic screws or plates, or a pacemaker). Splinting your joints for more than several days without professional evaluation is not advised. Although some disorders, notably fractures, require immobilization to heal, other disorders require mobilization for rapid, uncomplicated healing. Others require selective splinting with modification of work and sports until healed, sometimes accompanied by physiotherapy treatments. Micro fractures do occur with overuse, so be sure to have this evaluated properly. One of the most common complications of poorly treated bursitis, especially of the shoulder, is a frozen joint that would not have been a problem under good professional guidance. So, head to your family doctor for a professional evaluation. Do not try to treat this yourself any further. Editor's Note: 3. Could you let me know if there are any advances on Elhers Danlos? A close friend has the hyper mobility type and has yet to find anyone in the U.K. who can help her. — Linda F Attention fibromyalgia sufferers! Elhers-Danlos syndrome (EDS) is a group of congenital genetic disorders of connective tissue affecting skin, blood vessels and joints that is often misidentified as fibromyalgia until complications occur. There is no cure yet. Vitamin C has been touted as a treatment, but there is little supportive evidence. Gene translocation therapy and stem cell transplantation and research may offer a cure in the near future. At present, treatment is restricted to symptomatic relief and prevention of anticipated injury and reinjury. There are six major types, and all types affect joints with hypermobility — flexible joints that extend beyond the normal range of movement. (Remember that normal joints may be flexible or double-jointed, and this is not the same as EDS.) Hypermobility type EDS or Type 3 (old classification) is the most common variant affecting one in 10,000 to 15,000 individuals, and is often unrecognized by many health practitioners. Often misdiagnosed as fibromyalgia, this form of the syndrome often is not recognized until serious complications intervene because there are no specific commonly used blood tests to warn your doctor this may not be fibromyalgia! Associated pain is recognized as a serious complication, as it often heralds devastating and disabling complications. The National Organization for Rare Disorders (http://www.rarediseases.org) maintains a database of international EDS organizations you may find useful. Editor's Note: 4. Can injections of B12 stop the problem of continuous music being heard in the head? — Mary C. No, a B12 shot or supplementation of B12 will not cure the sensation of music in a person’s head. The noise could result from a metallic dental filling, crown, or bridge that is tuning in a local radio station (rare but well-documented) or could be auditory hallucinations. Such hallucinations are often the hallmark of schizophrenia, although they may be associated with drug (usually illicit) toxicity in very rare circumstances. The problem rarely is associated with prescription medications. Anyone suffering from this problem should go to his personal physician for an exam. Editor's Note: Editor's Notes:
Allopurinol as a novel drug in the treatment of bone cyst - Elsevier Allopurinol as a novel drug in the treatment of bone cyst. Hamid Namazia,. a
http://linkinghub.elsevier.com/retrieve/pii/S0306987706002556 ...Allopurinol prevents the release of a substance called xanthine oxidase, which helps in the formation of uric acid. In treatment for gout, ...
xanthine oxidase, an enzyme involved in purine metabolism. ...
Xanthine oxidase and the beneficial effect of allopurinol on blood ... authors attributed the benefits of allopurinol on blood pressure and renal function to the ... c by milk xanthine oxidase. J Biol Chem 243(21):5753–5760 ...
Phytochemistry : Glycosides and xanthine oxidase inhibitors from ...
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| 7120 | Lee & Cindy leeandcindy@... cheyennecin |
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| 4724 | Lee and Cindy leeandcindy@... cheyennecin |
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